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HANGZHOU FLYING TECHNOLOGY CO., LTD.

Products >> Toosendanin

Toosendanin

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Description
Product Name: Toosendanin
Supply Ability: 1000kg
Related proudcts
Specifications 25%-98%
Price Term: fob
Port of loading: air
Minimum Order 1kg
Unit Price: $1800

[Product name]: Toosendanin
[Plant Source]: CORTEX MELIAE
[Chemical name]: 1-isothiocyanato-4-(methyl-sulfinyl) butane
[Structural formula]: C30H38O11
[CAS Reg]: 79304-40-8
[Molecular weight]: 574.63
[Specification]: Toosendanin assay: 1.5�25%,98% (HPLC),or custom-made according to the customer request
[Main functions]:
Toosendanin (TSN), a tetranortriterpenoid compound from the plant Melia toosendan, has been reported to protect rats and non-human primates from the lethal actions of botulinum neurotoxin A (BoNT/A). TSN was tested in isolated mouse phrenic nerve-hemidiaphragm preparations against BoNT serotypes A, B and E. When added prior to toxin, TSN was found to delay the onset of muscle paralysis with all 3 BoNT serotypes. TSN had little or no effect on BoNT-induced muscle paralysis when applied 30 min after BoNT. It is suggested that the antagonist activity of TSN may result from inhibition of BoNT translocation

Contact Us
Company: HANGZHOU FLYING TECHNOLOGY CO., LTD.
Contact: Mr. jun gao
Address: Qingshan Industrial Park, Hangzhou City, Zhejiang Province, China.
Postcode: 310011
Tel: 086-571-87389059
Fax: 086-571-87389060
E-mail:         


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